Description:
Imipenem is an intravenous β-lactam antibiotic. It is the first member of the carbapenem class of antibiotics. Imipenem is discovered via a lengthy trial-and-error search for a more stable version of the natural product thienamycin, which is produced by the bacterium Streptomyces cattleya. Imipenem has a broad spectrum of activity against aerobic and anaerobic, Gram-positive and Gram-negative bacteria. It is particularly important for its activity against Pseudomonas aeruginosa and the Enterococcus species, but it is not active against MRSA.
- Molecular Weight: 317.36
- Molecular Formula: C12H17N3O4S.H2O
Purity: 98%
Canonical SMILES:
CC(C1C2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O.O
InChI:
InChI=1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
InChIKey: GSOSVVULSKVSLQ-JJVRHELESA-N
- Boiling Point: 567.3°C at 760 mmHg
- Melting Point: 193-198°C
- Solubility: Soluble in DMSO, Methanol
- Appearance: Off-white to Pale Yellow Solid
- Application: Anti-Bacterial Agents
- Storage: Store at -20°C
Synonyms:
(5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, monohydrate; N-Formimidoyl Thienamycin; MK-787; MK 787; MK787
More details are to be found on supplier website
